Prime .46 acre O&I (Office & Institutional) zoned lot located in the highly desirable midtown Wilmington corridor off Yaupon Drive. With approximately 100 feet of frontage and 200 feet of depth, this parcel offers an ideal footprint for a professional or medical office development. The lot size and configuration is believed to support approximately a 4,000-5,500 square foot building, subject to buyer verification based on specific use and site planning requirements, making it well-suited for medical, dental, legal, or other professional office users. Located just a short distance to the hospital and surrounded by established medical and dental offices, this property benefits from an existing healthcare corridor that supports long-term demand and convenience for both providers and patients. Ideal for a medical user seeking proximity to the hospital and an established provider base. Positioned in a transitional area with a mix of residential and office uses, the setting provides accessibility while maintaining a lower intensity environment preferred for office development. Opportunities like this are increasingly limited in this central location where demand for small office sites remains strong. Buyers are encouraged to verify permitted uses, parking requirements, and development standards with New Hanover County and the City of Wilmington.